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1.

16027
Accesses

Research article   Open Access Highly Accessed

Evaluation of Biologically Active Compounds from Calendula officinalis Flowers using Spectrophotometry

Monica Butnariu, Cristina Coradini Chemistry Central Journal 2012, 6:35 (27 April 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | Graphical abstract

2.

12584
Accesses

Research article   Open Access Highly Accessed

Cacao seeds are a "Super Fruit": A comparative analysis of various fruit powders and products

Stephen J Crozier, Amy G Preston, Jeffrey W Hurst, Mark J Payne, Julie Mann, Larry Hainly, Debra L Miller Chemistry Central Journal 2011, 5:5 (7 February 2011)

Abstract | Full text | PDF | PubMed

3.

12167
Accesses

Software   Open Access Highly Accessed

Avogadro: an advanced semantic chemical editor, visualization, and analysis platform

Marcus D Hanwell, Donald E Curtis, David C Lonie, Tim Vandermeersch, Eva Zurek, Geoffrey R Hutchison Journal of Cheminformatics 2012, 4:17 (13 August 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary | Graphical abstract

The Avogadro project has developed an advanced molecule editor and visualizer designed for cross-platform use in computational chemistry, molecular modeling, bioinformatics, materials science, and related areas.

4.

10169
Accesses

Preliminary communication   Open Access Highly Accessed

Different extraction methods of biologically active components from propolis: a preliminary study

Boryana Trusheva, Dorina Trunkova, Vassya Bankova Chemistry Central Journal 2007, 1:13 (7 June 2007)

Abstract | Full text | PDF | PubMed

5.

9749
Accesses

Perspectives   Open Access Highly Accessed

Toward a general theory of evolution: Extending Darwinian theory to inanimate matter

Addy Pross Journal of Systems Chemistry 2011, 2:1 (7 June 2011)

Abstract | Full text | PDF

6.

9328
Accesses

Research article   Open Access Highly Accessed

Preparation and magnetic properties of nano size nickel ferrite particles using hydrothermal method

Kamellia Nejati, Rezvanh Zabihi Chemistry Central Journal 2012, 6:23 (30 March 2012)

Abstract | Full text | PDF | PubMed | Graphical abstract

7.

8247
Accesses

Software   Open Access Highly Accessed

Open Babel: An open chemical toolbox

Noel M O'Boyle, Michael Banck, Craig A James, Chris Morley, Tim Vandermeersch, Geoffrey R Hutchison Journal of Cheminformatics 2011, 3:33 (7 October 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary | Graphical abstract

The first publication reporting the features, implementation and validation of the open source chemical toolbox - Open Babel - is described, which includes a summary of key advances in the 2.3 release

8.

8142
Accesses

Research article   Open Access Highly Accessed

An analysis of Sorghum halepense’s behavior in presence of tropane alkaloids from Datura stramonium extracts

Monica Butnariu Chemistry Central Journal 2012, 6:75 (28 July 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | Graphical abstract

9.

7076
Accesses

Research article   Open Access Highly Accessed

Heavy metals health risk assessment for population via consumption of vegetables grown in old mining area; a case study: Banat County, Romania

Monica Harmanescu, Liana Alda, Despina Bordean, Ioan Gogoasa, Iosif Gergen Chemistry Central Journal 2011, 5:64 (22 October 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | Graphical abstract

10.

6707
Accesses

Preliminary communication   Open Access Highly Accessed

Linked open drug data for pharmaceutical research and development

Matthias Samwald, Anja Jentzsch, Christopher Bouton, Claus Kallesøe, Egon Willighagen, Janos Hajagos, M Marshall, Eric Prud'hommeaux, Oktie Hassanzadeh, Elgar Pichler, Susie Stephens Journal of Cheminformatics 2011, 3:19 (16 May 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | Graphical abstract

11.

6397
Accesses

Research article   Open Access Highly Accessed

Estimation of synthetic accessibility score of drug-like molecules based on molecular complexity and fragment contributions

Peter Ertl, Ansgar Schuffenhauer Journal of Cheminformatics 2009, 1:8 (10 June 2009)

Abstract | Full text | PDF | PubMed | Graphical abstract

12.

6243
Accesses

Research article   Open Access Highly Accessed

Reverse phase chromatographic behaviour of major components in Capsicum Annuum extract

Monica Butnariu, Angela Caunii, Salomeia Putnoky Chemistry Central Journal 2012, 6:146 (4 December 2012)

Abstract | Full text | PDF | PubMed | Graphical abstract

13.

6192
Accesses

Research article   Open Access Highly Accessed

Effect of carboxymethyl cellulose concentration on physical properties of biodegradable cassava starch-based films

Wirongrong Tongdeesoontorn, Lisa J Mauer, Sasitorn Wongruong, Pensiri Sriburi, Pornchai Rachtanapun Chemistry Central Journal 2011, 5:6 (10 February 2011)

Abstract | Full text | PDF | PubMed

14.

6158
Accesses

Research article   Open Access Highly Accessed

Evaluation of phenolic contents and antioxidant activity of various solvent extracts of Sonchus asper (L.) Hill

Rahmat Khan, Muhammad Khan, Sumaira Sahreen, Mushtaq Ahmed Chemistry Central Journal 2012, 6:12 (6 February 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

15.

6118
Accesses

Research article   Open Access Highly Accessed

Investigation of antibacterial properties silver nanoparticles prepared via green method

Kamyar Shameli, Mansor Ahmad, Seyed Jazayeri, Parvaneh Shabanzadeh, Parvanh Sangpour, Hossein Jahangirian, Yadollah Gharayebi Chemistry Central Journal 2012, 6:73 (27 July 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary | Graphical abstract

A series of silver nanoparticles with varying sizes was prepared via a green method. All nanoparticles displayed antibacterial activity with the best activities observed for smaller nanoparticles

16.

6084
Accesses

Research   Open Access Highly Accessed

Algae biodiesel - a feasibility report

Yihe Gao, Chapin Gregor, Yuanjie Liang, Dawei Tang, Caitlin Tweed Chemistry Central Journal 2012, 6(Suppl 1):S1 (23 April 2012)

Abstract | Full text | PDF | PubMed

17.

6065
Accesses

Research article   Open Access Highly Accessed

Chemical analysis of Greek pollen - Antioxidant, antimicrobial and proteasome activation properties

Konstantia Graikou, Suzanne Kapeta, Nektarios Aligiannis, George Sotiroudis, Niki Chondrogianni, Efstathios Gonos, Ioanna Chinou Chemistry Central Journal 2011, 5:33 (23 June 2011)

Abstract | Full text | PDF | PubMed | Graphical abstract

18.

5956
Accesses

Methodology   Open Access Highly Accessed

The Molecule Cloud - compact visualization of large collections of molecules

Peter Ertl, Bernhard Rohde Journal of Cheminformatics 2012, 4:12 (6 July 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary | Graphical abstract

A new visualization technique is presented, which provides basic information about the composition of molecular data sets at a single glance.

19.

5767
Accesses

Research article   Open Access Highly Accessed

Open Data, Open Source and Open Standards in chemistry: The Blue Obelisk five years on

Noel M O'Boyle, Rajarshi Guha, Egon L Willighagen, Samuel E Adams, Jonathan Alvarsson, Jean-Claude Bradley, Igor V Filippov, Robert M Hanson, Marcus D Hanwell, Geoffrey R Hutchison, Craig A James, Nina Jeliazkova, Andrew SID Lang, Karol M Langner, David C Lonie, Daniel M Lowe, Jérôme Pansanel, Dmitry Pavlov, Ola Spjuth, Christoph Steinbeck, Adam L Tenderholt, Kevin J Theisen, Peter Murray-Rust Journal of Cheminformatics 2011, 3:37 (14 October 2011)

Abstract | Full text | PDF | PubMed |  Editor’s summary | Graphical abstract

The work carried out by the Blue Obelisk movement over the last five years is described, with a discussion of the current progress and future challenges in Open Data, Open Standards, and Open Source in chemistry

20.

5717
Accesses

Research article   Open Access Highly Accessed

Inhibition of Listeria monocytogenes ATCC 19115 on ham steak by tea bioactive compounds incorporated into chitosan-coated plastic films

Dan C Vodnar Chemistry Central Journal 2012, 6:74 (28 July 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary | Graphical abstract

Incorporation of tea extracts into antimicrobial films for vacuum packaged ham steaks considerably enhanced their effectiveness against L. monocytogenes - a common foodborne pathogen

21.

5343
Accesses

Research article   Open Access Highly Accessed

Antioxidant activity relationship of phenolic compounds in Hypericum perforatum L.

Dejan Z Orčić, Neda M Mimica-Dukić, Marina M Francišković, Slobodan S Petrović, Emilija Đ Jovin Chemistry Central Journal 2011, 5:34 (25 June 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | Graphical abstract

22.

5255
Accesses

Software   Open Access Highly Accessed

OMG: Open Molecule Generator

Julio E Peironcely, Miguel Rojas-Chertó, Davide Fichera, Theo Reijmers, Leon Coulier, Jean-Loup Faulon, Thomas Hankemeier Journal of Cheminformatics 2012, 4:21 (17 September 2012)

Abstract | Full text | PDF | PubMed | 1 comment

23.

5236
Accesses

Editorial   Open Access Highly Accessed

Welcome Home, Systems Chemists!

Günter von Kiedrowski, Sijbren Otto, Piet Herdewijn Journal of Systems Chemistry 2010, 1:1 (18 August 2010)

Abstract | Full text | PDF

24.

5093
Accesses

Research article   Open Access Highly Accessed

Microwave-assisted synthesis and antioxidant properties of hydrazinyl thiazolyl coumarin derivatives

Hasnah Osman, Afsheen Arshad, Chan Lam, Mark C Bagley Chemistry Central Journal 2012, 6:32 (17 April 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary | Graphical abstract

A series of coumarin derivatives with promising antioxidant properties was synthesised using a microwave-assisted method, with several of the compounds displaying significant radical scavenging activity

25.

4966
Accesses

Research article   Open Access Highly Accessed

Heavy metals health risk assessment for population via consumption of food crops and fruits in Owerri, South Eastern, Nigeria

Orish Orisakwe, John Nduka, Cecilia Amadi, Daniel Dike, Onyinyechi Bede Chemistry Central Journal 2012, 6:77 (1 August 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

26.

4913
Accesses

Research article   Open Access Highly Accessed

Virtual screening of bioassay data

Amanda C Schierz Journal of Cheminformatics 2009, 1:21 (22 December 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

27.

4840
Accesses

Review   Open Access Highly Accessed

Molecular structure input on the web

Peter Ertl Journal of Cheminformatics 2010, 2:1 (2 February 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment | Graphical abstract

28.

4641
Accesses

Research article   Open Access Highly Accessed

Rapid and mobile determination of alcoholic strength in wine, beer and spirits using a flow-through infrared sensor

Dirk W Lachenmeier, Rolf Godelmann, Markus Steiner, Bob Ansay, Jürgen Weigel, Gunther Krieg Chemistry Central Journal 2010, 4:5 (23 March 2010)

Abstract | Full text | PDF | PubMed | Graphical abstract

29.

4574
Accesses

Research article   Open Access Highly Accessed

Green tea increases the survival yield of Bifidobacteria in simulated gastrointestinal environment and during refrigerated conditions

Dan C Vodnar, Carmen Socaciu Chemistry Central Journal 2012, 6:61 (22 June 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | Graphical abstract

30.

4531
Accesses

Research article   Open Access Highly Accessed

Computer-assisted methods for molecular structure elucidation: realizing a spectroscopist's dream

Mikhail Elyashberg, Kirill Blinov, Sergey Molodtsov, Yegor Smurnyy, Antony J Williams, Tatiana Churanova Journal of Cheminformatics 2009, 1:3 (17 March 2009)

Abstract | Full text | PDF | PubMed | Graphical abstract

31.

4339
Accesses

Research article   Open Access Highly Accessed

Structure-based classification and ontology in chemistry

Janna Hastings, Despoina Magka, Colin Batchelor, Lian Duan, Robert Stevens, Marcus Ennis, Christoph Steinbeck Journal of Cheminformatics 2012, 4:8 (5 April 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

32.

4333
Accesses

Research article   Open Access Highly Accessed

Biomedical properties and preparation of iron oxide-dextran nanostructures by MAPLE technique

Carmen Ciobanu, Simona Iconaru, Eniko Gyorgy, Mihaela Radu, Marieta Costache, Anca Dinischiotu, Philippe Le Coustumer, Khalid Lafdi, Daniela Predoi Chemistry Central Journal 2012, 6:17 (13 March 2012)

Abstract | Full text | PDF | PubMed

33.

4330
Accesses

Research article   Open Access Highly Accessed

Study on the stability and antioxidant effect of the Allium ursinum watery extract

Salomeia Putnoky, Angela Caunii, Monica Butnariu Chemistry Central Journal 2013, 7:21 (1 February 2013)

Abstract | Full text | PDF | PubMed | Graphical abstract

34.

4280
Accesses

Research article   Open Access Highly Accessed

A novel method for spectrophotometric determination of pregabalin in pure form and in capsules

Alka Bali, Prateek Gaur Chemistry Central Journal 2011, 5:59 (7 October 2011)

Abstract | Full text | PDF | PubMed | Graphical abstract

35.

4245
Accesses

Research article   Open Access Highly Accessed

Carotenoids, total polyphenols and antioxidant activity of grapes (Vitis vinifera) cultivated in organic and conventional systems

Claudiu-Ioan Bunea, Nastasia Pop, Anca Babeş, Cristian Matea, Francisc V Dulf, Andrea Bunea Chemistry Central Journal 2012, 6:66 (4 July 2012)

Abstract | Full text | PDF | PubMed | Graphical abstract

36.

4197
Accesses

Review   Open Access Highly Accessed

Amorphous calcium phosphate and its application in dentistry

Jie Zhao, Yu Liu, Wei-bin Sun, Hai Zhang Chemistry Central Journal 2011, 5:40 (8 July 2011)

Abstract | Full text | PDF | PubMed

37.

4196
Accesses

Review   Open Access Highly Accessed

Chemistry in Second Life

Andrew SID Lang, Jean-Claude Bradley Chemistry Central Journal 2009, 3:14 (23 October 2009)

Abstract | Full text | PDF | PubMed | Graphical abstract

38.

4131
Accesses

Review   Open Access Highly Accessed

Carnosine: can understanding its actions on energy metabolism and protein homeostasis inform its therapeutic potential?

Alan R Hipkiss, Stephanie P Cartwright, Clare Bromley, Stephane R Gross, Roslyn M Bill Chemistry Central Journal 2013, 7:38 (25 February 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Carnosine, a compound found in meat, has a range of beneficial properties, and may aid in the treatment of Alzheimer’s, Parkinson’s and other age-related diseases. This review discusses the mechanisms that could accommodate the uniquely disparate effects of carnosine on cellular activity

39.

4117
Accesses

Review   Open Access Highly Accessed

Chemical consequences of cutaneous photoageing

Sarah A Thurstan, Neil K Gibbs, Abigail K Langton, Christopher EM Griffiths, Rachel EB Watson, Michael J Sherratt Chemistry Central Journal 2012, 6:34 (25 April 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

UV radiation exacerbates the intrinsic ageing of human skin, accelerating the onset of age-related changes, such as wrinkle formation. This review discusses experimental evidence for UV-mediated differential degradation of normally long lived dermal proteins

40.

4092
Accesses

Methodology   Open Access Highly Accessed

In-silico predictive mutagenicity model generation using supervised learning approaches

Abhik Seal, Anurag Passi, UC Abdul Jaleel, Open Source Drug Discovery Consortium, David J Wild Journal of Cheminformatics 2012, 4:10 (15 May 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

41.

4062
Accesses

Software   Open Access Highly Accessed

CheS-Mapper - Chemical Space Mapping and Visualization in 3D

Martin Gütlein, Andreas Karwath, Stefan Kramer Journal of Cheminformatics 2012, 4:7 (17 March 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Analyzing chemical datasets is an important task for understanding structure-property relationships. Visualization tools can help to better comprehend the correlations, and in this paper, an open-source tool for inspecting small molecule datasets is presented

42.

4048
Accesses

Research article   Open Access Highly Accessed

Impact of fermentation, drying, roasting and Dutch processing on flavan-3-ol stereochemistry in cacao beans and cocoa ingredients

W Jeffrey Hurst, Susann H Krake, Stephen C Bergmeier, Mark J Payne, Kenneth B Miller, David A Stuart Chemistry Central Journal 2011, 5:53 (14 September 2011)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The first comprehensive study of the impact of fermentation, drying, roasting and Dutch processing of cacao beans and cocoa ingredients by measuring the stereoisomers of epicatechin and catechin is described

43.

4032
Accesses

Review   Open Access Highly Accessed

Analytical methods applied to diverse types of Brazilian propolis

Alexandra Sawaya, Ildenize Barbosa da Silva Cunha, Maria Marcucci Chemistry Central Journal 2011, 5:27 (1 June 2011)

Abstract | Full text | PDF | PubMed

44.

3998
Accesses

Research article   Open Access Highly Accessed

A 50-year record of NOx and SO2 sources in precipitation in the Northern Rocky Mountains, USA

David L Naftz, Paul F Schuster, Craig A Johnson Geochemical Transactions 2011, 12:4 (7 March 2011)

Abstract | Full text | PDF | PubMed

45.

3992
Accesses

Methodology   Open Access Highly Accessed

Quantification of particle-induced inflammatory stress response: a novel approach for toxicity testing of earth materials

Andrea D Harrington, Stella E Tsirka, Martin AA Schoonen Geochemical Transactions 2012, 13:4 (18 April 2012)

Abstract | Full text | PDF | PubMed

46.

3943
Accesses

Research article   Open Access Highly Accessed

Design of optimal solvent for extraction of bio–active ingredients from six varieties of Medicago sativa

Angela Caunii, George Pribac, Ioana Grozea, Dorin Gaitin, Ionel Samfira Chemistry Central Journal 2012, 6:123 (26 October 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | Graphical abstract

47.

3872
Accesses

Research article   Open Access Highly Accessed

Inducing mineral precipitation in groundwater by addition of phosphate

Karen E Wright, Thomas Hartmann, Yoshiko Fujita Geochemical Transactions 2011, 12:8 (26 October 2011)

Abstract | Full text | PDF | PubMed | Graphical abstract

48.

3853
Accesses

Research article   Open Access Highly Accessed

Heavy metal ions in wines: meta-analysis of target hazard quotients reveal health risks

Declan P Naughton, Andrea Petróczi Chemistry Central Journal 2008, 2:22 (30 October 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment | Graphical abstract

49.

3840
Accesses

Research article   Open Access Highly Accessed

Hollow mesoporous silica nanoparticles for intracellular delivery of fluorescent dye

Huichen Guo, Haisheng Qian, Shiqi Sun, Dehui Sun, Hong Yin, Xuepeng Cai, Zaixin Liu, Jinyan Wu, Tao Jiang, Xiangtao Liu Chemistry Central Journal 2011, 5:1 (5 January 2011)

Abstract | Full text | PDF | PubMed | Graphical abstract

50.

3823
Accesses

Research article   Open Access Highly Accessed

Experimental Study of Cement - Sandstone/Shale - Brine - CO2 Interactions

Susan A Carroll, Walt W McNab, Sharon C Torres Geochemical Transactions 2011, 12:9 (11 November 2011)

Abstract | Full text | PDF | PubMed

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