1.
Characterizing the admixed African ancestry of African Americans
Fouad
Zakharia,
Analabha
Basu,
Devin
Absher,
Themistocles
L
Assimes,
Alan
S
Go,
Mark
A
Hlatky,
Carlos
Iribarren,
Joshua
W
Knowles,
Jun
Li,
Balasubramanian
Narasimhan,
Steven
Sidney,
Audrey
Southwick,
Richard
M
Myers,
Thomas
Quertermous,
Neil
Risch,
Hua
Tang
Genome Biology 2009, 10 :R141 (22 December 2009)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
|
Editor’s summary
Genome-wide SNP analyses reveal the admixed African genetic ancestry of African Americans.
2.
A survey of enabling technologies in synthetic biology
Linda
J
Kahl,
Drew
Endy
Journal of Biological Engineering 2013, 7 :13 (10 May 2013)
Abstract | Full text | PDF | PubMed
3.
Phenotype, donor age and gender affect function of human bone marrow-derived mesenchymal stromal cells
Georg
Siegel,
Torsten
Kluba,
Ursula
Hermanutz-Klein,
Karen
Bieback,
Hinnak
Northoff,
Richard
Schäfer
BMC Medicine 2013, 11 :146 (11 June 2013)
Abstract | Provisional PDF
| PubMed
|
Editor’s summary
Mesenchymal stromal cells have potential for clinical application in regenerative medicine, but have varying functional properties owing to donor age and gender, suggesting that identification of these factors are important for clinical use.
4.
Model-based Analysis of ChIP-Seq (MACS)
Yong
Zhang,
Tao
Liu,
Clifford
A
Meyer,
Jérôme
Eeckhoute,
David
S
Johnson,
Bradley
E
Bernstein,
Chad
Nusbaum,
Richard
M
Myers,
Myles
Brown,
Wei
Li,
X Shirley
Liu
Genome Biology 2008, 9 :R137 (17 September 2008)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
|
Editor’s summary
MACS performs model-based analysis of ChIP-Seq data generated by short read sequencers.
5.
The Stanford Health Assessment Questionnaire: Dimensions and Practical Applications
Bonnie
Bruce,
James
F
Fries
Health and Quality of Life Outcomes 2003, 1 :20 (9 June 2003)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
6.
The Transcription Factor Encyclopedia
Dimas
Yusuf,
Stefanie
L
Butland,
Magdalena
I
Swanson,
Eugene
Bolotin,
Amy
Ticoll,
Warren
A
Cheung,
Xiao
Cindy Zhang,
Christopher
TD
Dickman,
Debra
L
Fulton,
Jonathan
S
Lim,
Jake
M
Schnabl,
Oscar
HP
Ramos,
Mireille
Vasseur-Cognet,
Charles
N
de Leeuw,
Elizabeth
M
Simpson,
Gerhart
U
Ryffel,
Eric
W-F
Lam,
Ralf
Kist,
Miranda
SC
Wilson,
Raquel
Marco-Ferreres,
Jan
J
Brosens,
Leonardo
L
Beccari,
Paola
Bovolenta,
Bérénice
A
Benayoun,
Lara
J
Monteiro,
Helma
DC
Schwenen,
Lars
Grontved,
Elizabeth
Wederell,
Susanne
Mandrup,
Reiner
A
Veitia
et al.
Genome Biology 2012, 13 :R24 (29 March 2012)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central |
|
Editor’s summary
A high quality compendium of transcription factor data that allows researchers to add new data via a peer-review system
7.
Integrative analysis of the microbiome and metabolome of the human intestinal mucosal surface reveals exquisite inter-relationships
Ian
H
McHardy,
Maryam
Goudarzi,
Maomeng
Tong,
Paul
M
Ruegger,
Emma
Schwager,
John
R
Weger,
Thomas
G
Graeber,
Justin
L
Sonnenburg,
Steve
Horvath,
Curtis
Huttenhower,
Dermot
PB
McGovern,
Albert
J
Fornace,
James
Borneman,
Jonathan
Braun
Microbiome 2013, 1 :17 (5 June 2013)
Abstract | Full text | PDF
8.
Multiplicity of cerebrospinal fluid functions: New challenges in health and disease
Conrad
E
Johanson,
John
A
Duncan,
Petra
M
Klinge,
Thomas
Brinker,
Edward
G
Stopa,
Gerald
D
Silverberg
Cerebrospinal Fluid Research 2008, 5 :10 (14 May 2008)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
9.
A diagnostic window for the treatment of acute graft-versus-host disease prior to visible clinical symptoms in a murine model
Carina
A
Bäuerlein,
Simone
S
Riedel,
Jeanette
Baker,
Christian
Brede,
Ana-Laura
Garrote,
Martin
Chopra,
Miriam
Ritz,
Georg
F
Beilhack,
Stephan
Schulz,
Robert
Zeiser,
Paul
G
Schlegel,
Hermann
Einsele,
Robert
S
Negrin,
Andreas
Beilhack
BMC Medicine 2013, 11 :134 (21 May 2013)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
Alloreactive T cells are present in the blood 2 weeks before the onset of acute graft-versus-host disease (GVHD) symptoms in a mouse model, suggesting these cells could be measured to allow early diagnosis and timely therapeutic intervention.
10.
What determines cell size?
Wallace
F
Marshall,
Kevin
D
Young,
Matthew
Swaffer,
Elizabeth
Wood,
Paul
Nurse,
Akatsuki
Kimura,
Joseph
Frankel,
John
Wallingford,
Virginia
Walbot,
Xian
Qu,
Adrienne
HK
Roeder
BMC Biology 2012, 10 :101 (14 December 2012)
Abstract | Full text | PDF | PubMed |
|
Editor’s summary
In a Forum article in the Cell geometry series, ten experts in ten different systems explain why it matters what size a cell is, and offer ten different answers on how it is controlled – probably all of them right.
11.
Moving pictures of the human microbiome
J Gregory
Caporaso,
Christian
L
Lauber,
Elizabeth
K
Costello,
Donna
Berg-Lyons,
Antonio
Gonzalez,
Jesse
Stombaugh,
Dan
Knights,
Pawel
Gajer,
Jacques
Ravel,
Noah
Fierer,
Jeffrey
I
Gordon,
Rob
Knight
Genome Biology 2011, 12 :R50 (30 May 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology
|
Editor’s summary
The dynamism of microbiome populations is seen in daily samples from a landmark multi-body site, multi-individual study
12.
Discovery and validation of cell cycle arrest biomarkers in human acute kidney injury
Kianoush
Kashani,
Ali
Al-Khafaji,
Thomas
Ardiles,
Antonio
Artigas,
Sean
M
Bagshaw,
Max
Bell,
Azra
Bihorac,
Robert
Birkhahn,
Cynthia
M
Cely,
Lakhmir
S
Chawla,
Danielle
L
Davison,
Thorsten
Feldkamp,
Lui
G
Forni,
Michelle
Gong,
Kyle
J
Gunnerson,
Michael
Haase,
James
Hackett,
Patrick
M
Honore,
Eric
AJ
Hoste,
Olivier
Joannes-Boyau,
Michael
Joannidis,
Patrick
Kim,
Jay
L
Koyner,
Daniel
T
Laskowitz,
Matthew
E
Lissauer,
Gernot
Marx,
Peter
A
McCullough,
Scott
Mullaney,
Marlies
Ostermann,
Thomas
Rimmelé
et al.
Critical Care 2013, 17 :R25 (6 February 2013)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology
|
Editor’s summary
Urine TIMP-2, and IGFBP7, two novel biomarkers for risk stratification of acute kidney injury, have been discovered and validated in more than 1000 critically ill patients.
13.
Classification of human genomic regions based on experimentally determined binding sites of more than 100 transcription-related factors
Kevin
Y
Yip,
Chao
Cheng,
Nitin
Bhardwaj,
James
B
Brown,
Jing
Leng,
Anshul
Kundaje,
Joel
Rozowsky,
Ewan
Birney,
Peter
Bickel,
Michael
Snyder,
Mark
Gerstein
Genome Biology 2012, 13 :R48 (5 September 2012)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
|
Editor’s summary
Machine learning analysis of ENCODE data for 100 transcription factors reveals six classes of genomic regions
14.
Improvements in patient-reported outcomes with apremilast, an oral phosphodiesterase 4 inhibitor, in the treatment of moderate to severe psoriasis: results from a phase IIb randomized, controlled study
Vibeke
Strand,
David
Fiorentino,
ChiaChi
Hu,
Robert
M
Day,
Randall
M
Stevens,
Kim
A
Papp
Health and Quality of Life Outcomes 2013, 11 :82 (10 May 2013)
Abstract | Full text | PDF | PubMed
15.
Evaluation of lifestyle interventions to treat elevated cardiometabolic risk in primary care (E-LITE): a randomized controlled trial
Jun
Ma,
Abby
C
King,
Sandra
R
Wilson,
Lan
Xiao,
Randall
S
Stafford
BMC Family Practice 2009, 10 :71 (12 November 2009)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
16.
Informing DSM-5: biological boundaries between bipolar I disorder, schizoaffective disorder, and schizophrenia
Victoria
E
Cosgrove,
Trisha
Suppes
BMC Medicine 2013, 11 :127 (14 May 2013)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
Victoria Cosgrove and Trisha Suppes agree that boundaries between the diagnosis of bipolar disorder I, schizophrenia and schizoaffective disorder are preserved in the DSM-5 criteria, as there is not yet enough data to justify a continuous model of psychosis.
17.
Transcriptional profiling of long non-coding RNAs and novel transcribed regions across a diverse panel of archived human cancers
Alayne
L
Brunner,
Andrew
H
Beck,
Badreddin
Edris,
Robert
T
Sweeney,
Shirley
X
Zhu,
Rui
Li,
Kelli
Montgomery,
Sushama
Varma,
Thea
Gilks,
Xiangqian
Guo,
Joseph
W
Foley,
Daniela
M
Witten,
Craig
P
Giacomini,
Ryan
A
Flynn,
Jonathan
R
Pollack,
Robert
Tibshirani,
Howard
Y
Chang,
Matt
van de Rijn,
Robert
B
West
Genome Biology 2012, 13 :R75 (28 August 2012)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
|
Editor’s summary
Transcript sequencings from 64 solid tumours of 17 diagnostic classes reveals cancer-specific lncRNAs
18.
QualComp: a new lossy compressor for quality scores based on rate distortion theory
Idoia
Ochoa,
Himanshu
Asnani,
Dinesh
Bharadia,
Mainak
Chowdhury,
Tsachy
Weissman,
Golan
Yona
BMC Bioinformatics 2013, 14 :187 (8 June 2013)
Abstract | Provisional PDF
| PubMed
19.
Comparative analysis of mycobacterium and related actinomycetes yields insight into the evolution of mycobacterium tuberculosis pathogenesis
Abigail
McGuire,
Brian
Weiner,
Sang
Park,
Ilan
Wapinski,
Sahadevan
Raman,
Gregory
Dolganov,
Matthew
Peterson,
Robert
Riley,
Jeremy
Zucker,
Thomas
Abeel,
Jared
White,
Peter
Sisk,
Christian
Stolte,
Mike
Koehrsen,
Robert
T
Yamamoto,
Milena
Iacobelli-Martinez,
Matthew
J
Kidd,
Andreia
M
Maer,
Gary
K
Schoolnik,
Aviv
Regev,
James
Galagan
BMC Genomics 2012, 13 :120 (28 March 2012)
Abstract | Full text | PDF | PubMed
20.
Depression and Obstructive Sleep Apnea (OSA)
Carmen
M
Schröder,
Ruth
O'Hara
Annals of General Psychiatry 2005, 4 :13 (27 June 2005)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central |
21.
Modeling gene expression using chromatin features in various cellular contexts
Xianjun
Dong,
Melissa
C
Greven,
Anshul
Kundaje,
Sarah
Djebali,
James
B
Brown,
Chao
Cheng,
Thomas
R
Gingeras,
Mark
Gerstein,
Roderic
Guigó,
Ewan
Birney,
Zhiping
Weng
Genome Biology 2012, 13 :R53 (5 September 2012)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
|
Editor’s summary
Models for linking gene expression with chromatin features vary according to cellular context and RNA measurement method
22.
The mxd operon in Shewanella oneidensis MR-1 is induced in response to starvation and regulated by Arcs/Arca and Bara/Uvry
Jana
Müller,
Soni
Shukla,
Kathinka
A
Jost,
Alfred
M
Spormann
BMC Microbiology 2013, 13 :119 (27 May 2013)
Abstract | Provisional PDF
| PubMed
23.
Hormone-Sensitive Lipase Knockouts
Fredric
B
Kraemer,
Wen-Jun
Shen
Nutrition & Metabolism 2006, 3 :12 (10 February 2006)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
24.
Chimeric antigen receptor containing ICOS signaling domain mediates specific and efficient antitumor effect of T cells against EGFRvIII expressing glioma
Chan-Juan
Shen,
Yu-Xiu
Yang,
Ethan
Q
Han,
Na
Cao,
Yun-Fei
Wang,
Yi
Wang,
Ying-Ying
Zhao,
Li-Ming
Zhao,
Jian
Cui,
Puja
Gupta,
Albert
J
Wong,
Shuang-Yin
Han
Journal of Hematology & Oncology 2013, 6 :33 (9 May 2013)
Abstract | Full text | PDF | PubMed
25.
Small RNA pyrosequencing in the protozoan parasite Entamoeba histolytica
reveals strain-specific small RNAs that target virulence genes
Hanbang
Zhang,
Gretchen
M
Ehrenkaufer,
Neil
Hall,
Upinder
Singh
BMC Genomics 2013, 14 :53 (25 January 2013)
Abstract | Full text | PDF | PubMed